Role of glutathione and oxidative stress in phalloidin-induced cholestasis

"Background/aims: Biliary glutathione is an important generator of the bile-salt independent flow, and is known to be regulated by the hepatic glutathione availability. We investigated, in an acute model of phalloidin-induced cholestasis, biliary glutathione secretion and the role of hepatic glutathione, oxidative stress, and protein kinase c activation, which have been implicated in many hepatotoxin-induced … Continue reading Role of glutathione and oxidative stress in phalloidin-induced cholestasis